Information

Cheapest Alternatives to Frontline Flea Medication for Pets


L.C. has experience working with stray cats and managing their health and overall wellness.

In 2011, the patent for fipronil—the active ingredient in Frontline for dogs and cats—expired. Since then, there have been numerous generics available. But what are the cheapest generics for cats and dogs and how does fipronil work to control fleas and ticks?

After researching the generic choices, here are the best brands at the cheapest price, but first you should understand what kind of product this is.

It is important to discuss any kind of flea control and medication with your vet before changing products. Some products work well for some pets and not well for others. It is also important that each pet gets the correct dose.

Here is a review of the product and what to look for when choosing a generic alternative. Natural flea treatment alternatives are also discussed.

Fipronil for Dogs

Barricade Spot On Treatment for dogs contains 9.7% fipronil, the same amount as in the original Frontline brand. When looking for a generic alternative, you will want to make sure that it does contain this amount of the fipronil in order to be effective.

The chemical fipronil adheres to the oils found naturally in your dog's skin and will continue to be released for up to three months (for fleas) and up to a month (for ticks). The flea treatment can be applied every month if needed and this is recommended for those that live in high-infestation areas such as the southern United States.

Fipronil for Cats

Cats can also benefit from the ingredients found in Frontline alternatives. If your cat is an adult and over a certain minimum weight (usually 1.5 pounds), then the fipronil dosage is usually the same. Sentry tends to have the best deal, per dosage, for cats.

Fipronil also bonds with the natural oils found in the cat's skin and is stored in the hair follicles to be released over time.

Most cats respond well to the fipronil chemical and it can keep your cat flea-free for up to 3 months. If your cat goes outdoors, you may want to consider using the treatment every month.

How to Apply Topical Flea Medication

To apply topical flea medication, first read the package instructions or consult your vet for guidelines. Some medications need to be administered all in one place and some should be dotted along the back in three or four places.

If the topical is to be administered in one place:

  1. Part the hair at the back of the neck, in an area your pet can't lick.
  2. Make sure you can see the pet's skin.
  3. Squeeze all the contents directly on the skin, trying to get as little as possible on the fur.
  4. Discard the container and wash your hands.
  5. Monitor your pet for any adverse reaction and contact your vet if they develop vomiting or lethargy.

How to Apply Any Flea Topical

If the topical is to be administered in more than one place:

  1. Make sure you pet is calm and still.
  2. Start at the base of the neck and part the fur, exposing the skin.
  3. Squeeze a small amount of the medication in the spot.
  4. Move 4 to 6 inches down the spine, part the fur and repeat.
  5. Continue for the amount of application sites recommend on the package (usually 3 to 4).
  6. Discard the container and wash your hands.
  7. Monitor for your pet for any kind of reaction and contact your vet with concerns.

Other Considerations

As with any flea medication, fipronil is a toxin that is meant to control pests such as fleas and ticks. Although most animals are not bothered by the chemical, it is important to figure out what works for your individual pet and its needs.

If you have been treating your pet for years with Frontline or other fipronil products and begin to have problems with fleas, you may need to switch medications for six months to a year.

According to a 2008 study by Jill Maddison and Stephen Page, some fleas can develop a resistance to fipronil over time. By alternating medications, you can help to eliminate the ability of the insect to adapt and resist.

You can also add an oral medication such as Comfortis to boost the power and combat the fleas with two different products at once.

As always, ask your vet about the right treatment plan.

How Does Fipronil Work?

Once fipronil is ingested, it goes to work on the nervous systems of insects, targeting a chemical structure and glutamate-gated chloride receptors, something that mammals don't have (Wikipedia, fipronil).

Because the chemical is slow-acting, insects can infect their nests and lairs as well (a consideration when treating an insect such as a cockroach).

According to drsfostersmith.com, fipronil targets adult fleas, basically speeding up their nervous system before killing them. So if you are treating a pet that already has fleas, you may see the fleas running around at high speed on your pet before dying.

It is important to remember that fipronil does not target eggs or larva so, if you already have fleas, it may take several weeks for your pet to become completely flea free as the chemical targets them once they become adults.

What About Natural Alternatives?

Just as the market of natural products for people has exploded in the past few years, so has the market for pet products and alternative flea medications for cats and dogs.

Some have had good luck with products such as Diatomaceous (diametrious) Earth products which is a natural product that is toxic to insects but harmless to pets.

This product is usually fed to the animal or sprinkled in areas where there are flea infestations.

While with any product, you should consult your vet, my experience has been that this may work well in cooler climates or those that are not heavily infested.

People in humid and hot climates may have a harder time controlling fleas with just natural alternatives but it may be something viable to try if that is what you are interested in.

Other Natural Alternatives

According to PETA there are other natural alternatives you can try such as:

  • Black Walnut
  • Natural Flea Treats With Vitamin B
  • Sodium Borate
  • Daily Flea Combing
  • Herbal Shampoos
  • Vacuuming and Washing of Pet Bedding

Even if you need to use topicals to get you flea population under control, you can try the natural alternatives during lower flea infestation times or after the flea problem is under control.

Find What Works for Your Pet

If you are looking for a good alternative flea treatment at an affordable price for your cat or dog, the fipronil Frontline alternatives may be a good choice.

But remember that each pet is different and each pet needs its own health plan. While we all want to save money while keeping our pets healthy, we need to make sure that we are using the best flea treatment plant for them.

Just a few years ago, there were no effective flea treatments for pets that did not cost well over fifty dollars for even a three-dose box.

Thanks to patents expiring, good flea prevention and care is well within many different pet owners' reach and budgets.

Questions & Answers

Question: Where do you buy Fipronil the generic Frontline alternative?

Answer: You can get it online or in grocery stores. I also have seen it in discount department stores like Walmart or Target. Check the ingredients. There are many generic versions these days.

L C David (author) from Florida on March 21, 2017:

I don't think it does. I think it can help to deworm. To kill fleas on your pet it would need to be sprinkled on them for a period of time as well as in their bedding, etc. It is safe for your dog to eat but won't de-flea just by eating.

mogie on March 20, 2017:

How does DE kill fleas in you feed it to your pet? It doesn't make biting them taste bad so I don't understand.

L C David (author) from Florida on January 05, 2015:

Yes, sometimes it is good to switch up flea meds just to help fight resistance. Hope you find something that works for your cat and keeps her flea free!

Diana Grant from United Kingdom on January 05, 2015:

My vet has recently told me not to use Frontline, as fleas were becoming resistant to it, and my cat had spots on her skin, which were caused by an allergy to fleas. An injection cured that, and she is now on a stronger medication for fleas, but, being on prescription, it's very expensive. So it does seem, from your article, that if I use the strong one for six months until it's finished, I can then go back to Frontline

L C David (author) from Florida on July 11, 2014:

I have an article all about Comforts for cats. It is a great alternative for those looking for a prescription flea med that is not topical.

pours mom on July 11, 2014:

I have tried revolution on my cat each month. However the flea part runs out before the rest of product and my cat has gone nuts itching. When confortis came out I swore by it so when my vet suggested trying it with my cat I was all for it. Now I have a happy kitty who gets combed out regularly and I have been using natural ways to control fleas in home an itch free kitty is a happy kitty

Rose Clearfield from Milwaukee, Wisconsin on March 30, 2014:

Good to know! I haven't had to combat fleas in this house (I shouldn't say that too loudly), but it's good to have some affordable options in case I ever do. Thanks!

Ann1Az2 from Orange, Texas on March 24, 2014:

No, I haven't tried it, but I think Walmart has it. If not, I'll have to order it online. I may try it next. I did try nematodes one time and they worked for awhile, but once the ground dried out, they stopped working.

L C David (author) from Florida on March 23, 2014:

Ann1Az2, have you tried the Diatomaceous Earth I mention near the end of my article? I have some friends who swear by it. Thanks for mentioning some more methods and ideas for flea control.

Ann1Az2 from Orange, Texas on March 23, 2014:

I was using Revolution on my cats, but I didn't like their reaction to it. One of my cats was sort of lethargic for a day or so, not bad, but I didn't like it. So I stopped using pesticides and went to natural stuff. I sprinkled cedar chips around my mobile home and in my flower beds. I also used them under the cat's bedding (in a pillowcase where they can't get to it - it's Velcroed together). Last year I soaked lemons in water overnight which forms a really great lemon water that helped repel the fleas. And it had an added benefit - it got rid of the lice that was on one of my cats. It also makes their hair soft. Since cats do a lot of licking, I made sure I put plenty of it under their ears and on top of their neck where they can't reach. That way, I only had to reapply it about every 2 or 3 days.

I also brush my cats daily and use a flea comb. I also wipe down the surfaces where they lay all the time (not their beds) with a mixture of water and Clorox, and I mop the floor with it, too.

I live in southeast Texas, so it's important to note that all of this doesn't completely eliminate the fleas, but it does keep them down to a minimum and my cats aren't constantly scratching. It also helps that I don't have carpet. My cats don't go outside, but neighbors' cats and dogs bring the fleas into my yard and then I track them in. That's why I try to keep cedar around the door ways outside.

Sorry for going on so long - I really did enjoy your hub! And Frontline is a good product. In some cases, it's the only thing that works.

L C David (author) from Florida on March 23, 2014:

Definitely important to figure out what works for your individual pets. My first Siamese lost all his hair when I gave him Revolution so it really is dependent on the cats. I found he could only tolerate Advantage II.

Shauna L Bowling from Central Florida on March 23, 2014:

I hear you. I tried to go the cheap route and one of my longhairs has lost half her hair. She's obviously allergic to fleas. I've got them back on the Revolution and her hair is now starting to grow back.

L C David (author) from Florida on March 23, 2014:

Yes. In Florida preventing mosquitoes really does make sense. I wish it wasn't so expensive though.

Shauna L Bowling from Central Florida on March 23, 2014:

Interesting info. I use Revolution on my cats. It also combats mosquitoes, which can cause heart-worm. It's expensive, but works better than anything else I've tried. It can only be obtained thru your vet because it requires a script.


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Buying guide for best dog flea and tick prevention

For many people, dogs really are man’s best friend – which is why we go to such great lengths to take care of them. But as much as you might worry about what you feed your favorite four-legged pal or what leash works best for those long walks, you definitely shouldn’t overlook the importance of finding a good flea and tick prevention product for Fido.

That’s because the right flea and tick prevention product can keep your dog safe from pests that could potentially cause health issues. Fleas and ticks could be lurking just about anywhere your buddy plays and spends time with other dogs – on walks, at the park, in the yard.

There are so many flea and tick products on the market for dogs today that choosing the best option can get a little overwhelming. Which formula is right for your particular pet? At BestReviews, we can answer this and other questions you may have about selecting a flea and tick prevention product for your dog.


Flea Control: Safe Solutions

From collars to sprays to topical solutions, Americans spend millions of dollars on flea-control products every year and unwittingly poison themselves and their animal companions. 1 There are safer, more environmentally friendly ways to protect your furry friends and yourself from these pesky insects.

Why Most Flea-Control Products Are Dangerous
The most popular kind of flea control product on the market is the “spot-on” variety, sold under brand names like Frontline ® and Advantage™. The active ingredients in these solutions include chemicals such as imidacloprid, fipronil, permethrin, methoprene, and pyriproxyfen, all of which have caused serious health problems in animals in laboratories. 2 Even some of the inert ingredients can be hazardous to your animal companion’s health. In 2009, the Environmental Protection Agency received complaints of “adverse reactions” ranging from skin irritation to seizures and death, and has since been “pursuing a series of actions to increase the safety of spot-on pesticide products for flea and tick control for cats and dogs.”which has included calls for tighter regulations and more comprehensive labeling. 3

Another popular form of flea control is the chewable tablet. The U.S. Food and Drug Administration (FDA) issued a warning about the isoxazoline class of flea and tick products, used in brand names Bravecto ® , Credelio ® , Nexgard ® and Simparica ® . Warning of the “potential for neurologic adverse events in dogs and cats…including muscle tremors, ataxia, and seizures,” the agency advises animal guardians to consult with their veterinarians before using these products. 4 These tablets also have been found less effective than topicals. 5

Other forms of flea control—powders, collars, and sprays—are no less dangerous to you or your companion animals. Labels may warn not to get these substances on your skin, to wash your hands after applying them, and to keep them away from children, yet these chemicals are absorbed by your animal’s skin. Immediate effects of pesticide overdose include vomiting, diarrhea, trembling, seizures, and respiratory problems. If your dog or cat shows any of these symptoms after the application of a pesticide, immediately wash the product off and seek veterinary care.

Put Out an ‘Unwelcome’ Mat
The first step in flea prevention lies in maintaining your dog or cat’s health. Skin condition is an indicator of an animal’s overall health and an important factor in flea control. The key to healthy skin is a healthy diet. Check food labels carefully. Pet foods sold in supermarkets are often composed of ground-up parts of animals deemed by the U.S. Department of Agriculture to be unfit for human consumption. This is usually listed among the ingredients on the label as “byproducts.” The flesh of animals who fall into one of the categories of the “four Ds”—dead, dying, diseased, or disabled—is what often goes into pet food. Many of these animals have died from infections and other diseases. Most commercial pet food contains the same hormones, pesticides, and antibiotics that are found in meat products for humans.

Just as important as what should be left out of an animal’s diet is what should be included in it. Fresh, whole, raw foods are vital because they provide digestive enzymes and vitamins that can be destroyed by cooking. Vitamin C and B-complex vitamins as well as essential fatty acids are needed for a healthy coat. And coconut oil, which contains caprylic acid, is excellent for combating yeast infections on the skin and in the ears. (Just add it to food.) Also include digestive enzymes and probiotics for good digestive health, which can affect the skin.

If You Have a Flea Problem
Effective flea-control programs employ a multifaceted approach that treats the environment as well as the animal. The following are nontoxic and natural ways that you can help control fleas:

• Black walnut is a very effective flea repellent for dogs when given orally several times a week. It can be purchased in capsules or in liquid form. Give only the minimum effective dose because it can be toxic in higher doses.
• A fine-toothed flea comb is essential and should be used daily to catch fleas. Keep a bowl of soapy water on hand and dip the comb into it after each sweep, or catch the fleas, put them in a container, and then freeze it.
• Vacuum rugs and furniture frequently and launder animals’ bed covers weekly, if necessary, during the flea season. Flea eggs can be collected by vacuuming but can still hatch in the bag, which should be sealed and thrown away, or put in the freezer in a plastic bag after each vacuuming.
• Diatomaceous earth, a powder composed of the fossilized remains of single-celled algae, can be sprinkled on carpets to eliminate fleas safely. Diatomaceous earth is harmless if ingested but should not be inhaled. When applying, remove animals from the area and wear a protective mask. Let the powder sit at least several hours before vacuuming. Look for diatomaceous earth at garden, animal supply, home improvement, and health-food stores, but never use diatomaceous earth that has been chemically treated for use in swimming pools. Ordinary table salt or borax can also be used on carpets and should be vacuumed up the day after use.
• A company called Rx for Fleas (1-800-666-3532) uses a patented nontoxic sodium borate compound that it guarantees for up to one year.
• Products containing beneficial nematodes (microorganisms that eat flea larvae) can be sprayed on lawns and, unlike many toxic treatments, are perfectly safe for animals, birds, and humans, as well as “friendly” garden dwellers, such as earthworms and ladybugs. Brand names such as Interrupt can be found in pet stores and in the lawn-and-garden sections of hardware stores and supermarkets.
• Gentle herbal shampoos are effective and can be used as often as once a week, although too-frequent bathing can dry out animals’ skin. When shampooing, use warm water and begin with a ring of lather around the animal’s neck so that fleas cannot climb onto the animal’s face. Flea-pesticide shampoos and dips are dangerous and are not necessary because soap and water kills fleas.
• To make an effective natural insect repellent for dogs that can be applied daily, add five drops each of tea tree oil, citronella oil, rosemary oil, peppermint oil, and eucalyptus oil to one cup of water, shake it, and put it in a spray bottle. (This smells great, too.)

The Heavy Artillery
For some dogs and cats, just one flea bite can trigger an uncomfortable and damaging skin reaction, so even stronger flea control may be necessary. Insect growth regulators (IGRs), although unfortunately required by law to be tested on animals, are a safe alternative to pesticides. Sold under the brand names Ovitrol, Fleatrol, Precor, and Archer, IGRs contain insect hormones that disrupt the life cycle of the flea by preventing eggs and larvae from developing into adults. IGRs are available from “pest”-control supply companies as well as companion animal supply stores, catalogs, and online. They should be applied to carpets and wooden floors—but not to animals. Another IGR, Program® (lufenuron), is administered to animals orally once a month. However, some animals have suffered adverse reactions to this and other long-term flea control products, so they should be considered for use only in extreme cases.

Where to Find Nontoxic Flea Control Products
• Natural Animal: 1-800-274-7387
• Only Natural Pet Store: 1-888-937-6677
• Pet Sage: 1-800-PET-HLTH


Fleas and ticks are not “just” bloodthirsty parasites. As if the fact that they’ll send your dog into a scratching frenzy isn’t enough to make them a nuisance, both ticks and fleas can cause serious health issues. If your pooch swallows a flea when trying to bite the itchiness away (and he will), he will get infested with tapeworms . Anemia, hot spots, and Bartonella infection are also possibilities for dogs infested with fleas.

Ticks are even worse- from paralysis to Lyme disease, Rocky Mountain Spotted Fever, and many other potentially fatal conditions, there’s no shortage to troubles these tiny bloodsuckers could cause. To avoid having to deal with the dangerous and often costly consequences of flea and tick infestations , it’s best to rely on flea and tick prevention medication.

What To Do To Repel Ticks from Dogs?

The best way to make sure your four-legged companion doesn’t contract a serious tick-borne disease is to use tick prevention medication. Really, there is no other way to be safe. But, even after you’ve applied the spot on or secured the collar, your job is not done. Sometimes, these products can malfunction and you’ll unknowingly leave your pet vulnerable. This often happens when the flea and tick prevention medication is not applied properly. For instance, your pet might have vomited his chewable treatment before it got absorbed, or they’ve been in the rain or swimming shortly after their spot on was applied. Mistakes happen, it’s only natural, so always make sure to be vigilant, even with the necessary precautions taken.

Avoid areas with tall grass or shrubby wooded areas where ticks could be thriving. Regularly inspect your pet for signs of ticks and if you happen to spot one- remove it properly and keep the dead tick so your vet could identify it if need be.

What is the Best Way to Get Rid of Fleas?

Dog fleas are a common occurrence- and an extremely frustrating one, as well. These tiny parasites make a home in your dog’s fur, feeding on their blood and making your pet’s life miserable in the process. The lifespan of a dog flea is between one and two weeks, but they reproduce and multiply at an alarming rate, so if you spot a few of them on your pet’s coat, you can bet they’ll turn to dozens in a blink of an eye. Needless to say, no pooch likes the biting of the fleas, which results in incessant scratching licking and counter-biting in an effort to exterminate the pests that are bothering them.

In the best-case scenario, the dog will just be driven crazy by the fleas and scratch like a maniac until you take things into your own hands. Some dogs are allergic to flea saliva, as well, so all of their symptoms will be far more severe. But in the worst case, they can open wound on their skin, contract an internal parasite, or infection before you turn to flea medication.

In other words, fleas will make your dog’s life a living hell, no matter how you look at it. Sadly, it’s not difficult for a dog to be infested with fleas as they can be picked up on every corner, but getting rid of them can be much harder than you’d expect. Eradicating fleas from your dog’s and your life takes the right tools, time, and a lot of patience. The first step is, naturally, treating your pet. But it’s not just about putting on a collar or spot on treatment or shampooing your pet. Flea eradication is a multi-step process that includes the environment as well.

The flea treatment you use on your pet will depend on a lot of things. You might want combined flea and tick medication treatment for full coverage, or just something that kills the fleas- or somethings that kills and repels. There are a lot of options to choose from! In the case you are looking to protect your pet in advance, a preventative such as a spot on or a collar will be enough, However, if the pets are already infested by the little buggers, you’ll have to use household treatments as well. Thorough vacuuming of the house and washing your pet’s bed is a must before you spray it all with a household flea treatment . This makes sure that the life cycle of the flea is disrupted and the larvae don’t get the chance to develop.

Types of Flea and Tick Prevention Medication Products

Now that you know how hard it is to get rid of fleas, and we all know that tick-borne diseases are no joke, it’s easy to see why prevention is crucial. Repelling fleas and ticks before they get the chance to endanger your pet’s health should be one of your primary concerns- year-round. So what are your options when it comes to flea and tick prevention medication? The main difference between the types of these products is the method of application, so you can choose between topical and edible preventatives.

Topical flea and tick prevention medication

Flea and tick repellent collars, spot on treatments, shampoos, sprays, and powders: there are plenty of ways to prevent fleas and ticks from feasting on your pet, but not all are equally effective. Some are suitable for adult dogs only (sorry puppies!), others are too mild for an adult to use, and some can be dangerous if your pet has certain allergies and sensitivities- Collies are particularly susceptible. The choice can be overwhelming, but most products have their specific uses and applications, so it’s mostly a matter of preference and the direness of the situation. For instance, if you are worried that your pet will lose his collar or that his lifestyle will render it ineffective, a spot on might be a better solution. And so on- each dog is unique and you should tailor your choice in accordance with their needs and quirks.

Edible flea and tick prevention medication

Chewables for flea and tick treatments are one of the newest and most popular choices. Your pooch gets a beef-flavored treat and with it, a month’s worth of protection from all types of parasites (including heartworm), as well as instant action in case of infestation. However, this type of preventative has to be taken only after a consult with a veterinarian and after you’ve done the test for heartworm.

So you see, not all flea and tick prevention medication products are created equal. Read on to find out which of them are worth your money and will deliver on their promises!

1.NexGard Chewable Tablets for Dogs

One of the worst parts about any type of medication for dogs is that you have to make them take it. Seriously, most dogs will sniff a tablet a mile away and not even wrapping it in bacon could help mask the chemical scent. Luckily, with Nexgard flea and tick prevention medication, you won’t have such problems. This bite-sized beef-flavored chewable tablet can be given to dogs as a snack- they’ll gladly gobble it up!

The fast-acting formula of these chewable tablets kills adult fleas before they can lay eggs in your pet’s coat, as well as any black-legged tick, American dog tick, Lone Star tick and brown dog tick that might be attached to your pooch. When given monthly, NexGard Chewable Tablets can offer year-round protection for your pet.

2. Frontline Plus Flea & Tick Treatment

This topical flea and tick prevention medication also kills chewing lice and mites with its improved formula. But, unlike many products on the market, Frontline Plus doesn’t just kill the adult fleas-it will also kill the next generation of larvae and eggs that could be infesting your dog. By stopping the further reproduction of the parasites, this spot-on breaks the flea life cycle for good. Granted, that’s only if you use it regularly on your pet- Frontline Plus will keep them safe from pests for 30 days straight, but after that, you’ll need to apply another dose.

The product is easy to apply and you won’t have to be a whiz to get your pooch comfortable with the process. Simply part your dog’s hair between their shoulder blades and use the plastic applicator to “pour” the contents in one spot. It’s important to do it this way to prevent your pooch from licking it- this would be very dangerous for them. While this is a waterproof flea and tick prevention medication, this applies only after the first 24 hours. Don’t let your pooch get wet until a day passes if you want this spot on to be efficient!

3. Brewer’s Yeast and Garlic Natural Flea & Tick Repellent Chewable Supplement

If you prefer natural alternatives over traditional options, you’ll love these veterinarian-formulated chewable tablets. Based on brewer’s yeast and garlic, these supplements for dogs promise to keep your pooch pest-free with natural ingredients. The idea behind it is that, by daily consumption of yeast and garlic tablets , dogs develop a scent that makes them extremely unappetizing to bloodsuckers. Humans and other dogs reportedly can’t register the odor, but fleas and ticks are repelled by it. To boot, the tablets are also an excellent source of protein, trace minerals, and B-complex vitamins that will support your pet’s overall health and improve the look of their coat.

Another great thing about this product is that it’s a part of the fantastic Project Paws – buying one pack of these chewable tablets will help provide 7 meals for shelter dogs. Fighting parasites and feeding pooches in need- a pawesome combo!

4. Sentry FiproGuard Topical Flea and Tick Prevention for Dogs

One of the more affordable flea and tick prevention medication for dogs, the Sentry FiproGuard kills the pests within few hours of application. Same like the Frontline Plus and many other brand names, this budget-friendly spot on uses fipronil to kill fleas, ticks, and chewing lice. It will efficiently eliminate brown dog ticks, American dog ticks, lone star ticks, and deer ticks. The formula protects your pet for four weeks, and the six month’s worth of this flea and tick prevention spot on costs under $20. And that’s for a large breed dog- like with most other spot on products, there are options for dogs of all sizes.

The spot on should be applied with an applicator, on several spots from the back of the neck to a point midway between the neck and tail. To make sure that it works as advertised, don’t bathe your pooch for 24 to 48 hours after the application.

5. K9 Advantix II Flea, Tick & Mosquito Prevention

It’s hard to beat K9 Advantix II when it comes to the spectrum of pests and parasites it fights off with a single product. This spot on antiparasitic will kill all life stages of fleas, from eggs and larvae to adult parasites, effectively ending their life cycle and preventing re-infestation by younger generations. Additionally, it will kill ticks and lice, as well as repel biting flies and mosquitoes from your four-legged friend. This makes it a great all-around flea and tick prevention medication with a broader spectrum of effect than you’d usually expect.

This particular spot on is made to be used on extra large dog breeds or those pooches that weigh a minimum of 55 pounds. Fortunately, this powerful flea and tick prevention medication is also available for large, medium, and small dogs- every doggo can get the pest protection they deserve!

6. Provecta Advanced For Dogs

This once-a-month topical prevention and treatment for dogs is touted as the more affordable alternative to K9 Advantix II. Both products contain the same ingredients- imidacloprid, permethrin and pyriproxyfen, an insect growth regulator. The jury is still out on the efficiency of the two competitors, but the majority agrees that Provecta gives you good bang for your buck. It repels and kills ticks, fleas, chewing lice, biting flies, and mosquitos in all of their life stages. With regular use, this topical prevention product could keep your pooch pest-free for the whole year.

In case you have a couple of fur babies in your family, this budget-friendly spot on could be a good solution for you. The savings could be significant- especially on a yearly level.

7. Onguard Flea & Tick Treatment for Dogs

This dual action flea and tick treatment works to kill the existing parasites on your pet and to prevent future generations of pests making a home in your dog’s fur. To achieve this, Onguard spot on is using the same active ingredients as Frontline Plus does- fipronil and (S)-methoprene. Fipronil works to instantly eliminate adult ticks and fleas present on the dog, whereas the (S)-methoprene disrupts the maturation of flea larvae and eggs, preventing them from developing into adult parasites. In addition to killing all pests on your pet, it will repel them for up to 30 days. After that, you’ll need to re-apply the solution to make sure that the protection is continuous.

8. Vectra 3D Broad Spectrum Flea and Tick Treatment

This topical solution repels and kills fleas, ticks, mosquitoes, biting and sand flies, lice and mites (excluding mange mites). A truly broad spectrum parasite prevention and treatment, Vectra 3D will keep your pet protected for 30 days after you apply it. The fact that it repels and kills parasites improves your pet’s odds of never being bitten in the first place, and minimizes the risk for contracting a disease. Of course, that’s only in case your pet is not already infested.

The fast-working active ingredients will kill fleas in all life stages in as little as 6 hours after the spot on is applied.

9. GreenFort NEO Bio Spot-On

If your four-legged bestie is sensitive to most active ingredients in conventional flea and tick prevention medication products, or you simply favor natural products, this spot on might be right up your alley. The formula of this spot on uses essential oils to repel pests away from your doggo- especially those with a strong citrus scent.

The bio-based product promises to chase away fleas, ticks, withers, mosquitoes, flies, and horseflies. The longevity will vary from 14 to 30 days- or until the scent loses its potency.

10. Simparica Chewable Tablets for Dogs

One tasty bite and your dog is protected from fleas and ticks for up to 35 days! These chewable tablets kill and repel fleas in all life stages, as well as four types of ticks – Lone Star tick, Gulf Coast tick, American dog tick, and brown dog tick. This package contains 6 treatments, so your furbaby will be free of pests for half a year with just one purchase. Plus, it doesn’t hurt that the tablets are liver-flavored- they’ll be a yummy treat for your pet so you won’t have to mask the tablet with food to trick them into eating it!

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Watch the video: Dog owners blame popular flea medicine for petss deaths (September 2021).